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Certified Pharmacy Technician (CPhT) Practice Exam

Certified Pharmacy Technician (CPhT)

About Certified Pharmacy Technician (CPhT)

Certified Pharmacy Technician (CPhT) is the foundation of a rewarding career as a pharmacy technician. The certification is an important first step toward a rewarding career in healthcare. As a CPhT, you can work effectively to support your pharmacy team and provide superior patient care.


Prerequisite for the exam

  • Completion of a PTCB-Recognized Education/Training Program or equivalent work experience
  • Full disclosure of all criminal and State Board of Pharmacy registration or licensure actions
  • Compliance with all applicable PTCB Certification policies
  • Passing score on the Pharmacy Technician Certification Exam


Exam Structure

1. Domain 1: Medications (40%)

Generic names, brand names, and classifications of medications 

Therapeutic equivalence

Common and life-threatening drug interactions and contraindications (e.g., drug-disease, drug-drug, drug-dietary supplement, drug-laboratory, drug-nutrient)

Strengths/dose, dosage forms, routes of administration, special handling and administration instructions, and duration of drug therapy

Common and severe medication side effects, adverse effects, and allergies

Indications of medications and dietary supplements

Drug stability (e.g., oral suspensions, insulin, reconstitutables, injectables, vaccinations)

Narrow therapeutic index (NTI) medications

Physical and chemical incompatibilities related to non-sterile compounding and reconstitution 

Proper storage of medications (e.g., temperature ranges, light sensitivity, restricted access)

2. Domain 2: Federal Requirements (12.5%)

Federal requirements for handling and disposal of non-hazardous, hazardous, and pharmaceutical substances and waste

Federal requirements for controlled substance prescriptions (i.e., new, refill, transfer) and DEA controlled substance schedules

Federal requirements (e.g., DEA, FDA) for controlled substances (i.e., receiving, storing, ordering, labeling, dispensing, reverse distribution, take-back programs, and loss or theft of)

Federal requirements for restricted drug programs and related medication processing (e.g., pseudoephedrine, Risk Evaluation and Mitigation Strategies [REMS])

FDA recall requirements (e.g., medications, devices, supplies, supplements, classifications)

3. Domain 3: Patient Safety and Quality Assurance (26.25%)

High-alert/risk medications and look-alike/sound-alike [LASA] medications

Error prevention strategies (e.g., prescription or medication order to correct patient, Tall Man lettering, separating inventory, leading and trailing zeros, bar code usage, limit use of error-prone abbreviations)

Issues that require pharmacist intervention (e.g., drug utilization review [DUR], adverse drug event [ADE], OTC recommendation, therapeutic substitution, misuse, adherence, post-immunization follow-up, allergies, drug interactions)

Event reporting procedures (e.g., medication errors, adverse effects, and product integrity, MedWatch, near miss, root-cause analysis [RCA])

Types of prescription errors (e.g., abnormal doses, early refill, incorrect quantity, incorrect patient, incorrect drug)

Hygiene and cleaning standards (e.g., handwashing, personal protective equipment [PPE], cleaning counting trays, countertop, and equipment)

4. Domain 4: Order Entry and Processing (21.25%) 

Procedures to compound non-sterile products (e.g., ointments, mixtures, liquids, emulsions, suppositories, enemas)

Formulas, calculations, ratios, proportions, alligations, conversions, Sig codes (e.g., b.i.d.k, t.i.d., Roman numerals), abbreviations, medical terminology, and symbols for days supply, quantity, dose, concentration, dilutions

Equipment/supplies required for drug administration (e.g., package size, unit dose, diabetic supplies, spacers, oral and injectable syringes)

Lot numbers, expiration dates, and National Drug Code (NDC) numbers

Procedures for identifying and returning dispensable, non-dispensable, and expired medications and supplies (e.g., credit return, return to stock, reverse distribution)


Exam Pattern

  • Exam Name: Certified Pharmacy Technician (CPhT)
  • Length of Time: 2 Hours


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What are our Practice Exams?

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  • Practice exam questions have been created on the basis of content outlined in the official documentation.
  • Each set in the practice exam contains unique questions built with the intent to provide real-time experience to the candidates as well as gain more confidence during exam preparation.
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